Endocrine Abstracts

Aim: The aim of this study is evaluating trabecular bone score (TBS) and bone mineral density (BMD) in normal women depending on duration of postmenopausal period (PMP).Materials and methods: We’ve examined 122 normal women aged 40–79 years (mean age – 56.2±0.8 years; mean height – 162.6±0.5 cm; mean weight – 71.5±1.3 kg), who were divided into the groups depending on duration of PMP: without menopause (with normal...

Introduction: The consequences of vitamin D deficiency are secondary hyperparathyroidism and bone loss, leading to osteoporosis and fractures, mineralization defects, which may lead to osteomalacia in the long term, and muscle weakness, causing falls and fractures.Objectives: The aim of the research was to determine the frequency of vitamin D deficiency, secondary hyperparathyroidism and it’s influence on bone mineral density in people of different ...

Aim: The aim of this study is evaluating of body composition and frequency of sarcopenia in women depending on age.Materials and methods: We’ve examined 8637 women aged 20–89 years (mean age – 56.7±0.14 years; mean height – 162.5±0.07 cm; mean weight – 73.5±0.16 kg). The patients were divided into two groups depending on age: 20–24 (n=143), 25–29 (n=209), 30–34 (n=271), 35&...

The aim of the study was to evaluate the influence of high levels of thyroid hormones on bone mineral density in male rats as a function of experimental hyperthyroidism duration and age.Research object: Research is conducted on 56 white male rats of ‘Wistar’ breed. There were three age-dependent groups (1.5 month rats are pre-pubertal, 5–6 month are reproductive animals and 24 month – old). Animals were subdivided into 6 groups: group...

Thyrotoxicosis has been linked to osteoporosis and increased fracture risk. On the other hand, decreasing serum levels of estrogens in postmenopausal women potentially may increase effect of thyroid hormones on bone tissue. Dual-energy X-ray absorptiometry is an accurate and precise method of determining BMD, and has been wildly-used for diagnosing osteopenia and osteoporosis. The aim of our study was to study by means of DXA the peculiarities of bone loss in women of differen...

Menopause is a special period in women’s life when various physiological changes occur, for example, dyslipidemia, atherosclerosis, and decrease of BMD. During menopause, atherosclerosis and osteoporosis develop simultaneously. This period is typically characterized by increasing frequency of ischemic heart disease and myocardial infarction. The risk factors including atherogenic dyslipidemia, insulin resistance, smoking, low physical activity are common for the developme...

Objective: Menopause-related changes in female body are associated with the greater risk of metabolic syndrome (MS), which includes obesity, dyslipidemia, impaired glucose tolerance, hypertension.Aim: The purpose of our study was to reveal peculiarities of fat and lean mass distribution between postmenopausal women with abdominal obesity and with MS.Design and Method: The sample consisted of 43 postmenopausal 60–69 years old w...

Aim: To evaluate the effect of strontium ranelate in treatment of systemic osteoporosis in postmenopausal women.Materials and methods: There were examined 82 postmenopausal women with systemic osteoporosis (average age 58.4±4.5 years). Evaluation of pain syndrome and level of physical activity was carried out with VAS (the questionnaire developed by the ‘Servier’ company). Bone mineral density (BMD) was determined by means of dual-energy X...

Objective: The metabolic syndrome (MS), which includes obesity, dyslipidemia, impaired glucose tolerance, and hypertension, is a major public health problem. The prevalence of MS among women in postmenopausal period is nearly 24%. In postmenopausal period the accelerated bone loss, contributing to the development of osteoporosis begins. Obesity or increased body mass index (BMI) is known to have a protective effect against osteoporosis. However, recent studies demonstrated tha...